产品货号:
Z11605
中文名称:
ATG7抗体
英文名称:
Anti-ATG7 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ATG7 Antibody |
指标别名 | APG7 LIKE;APG7L;ATG7;Autophagy related protein 7;GSA7;hAGP7 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | ELISA,WB,ICC,IF |
基因名称 | ATG7 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | APG7 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human APG7.The immunogen is located within amino acids 590 - 640 of APG7. |
计算分子量 | 78kDa |
成分 | APG7 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | APG7 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Autophagy,the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells.It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components.This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1.Another member of the autophagy family of proteins is APG7 which was identified in yeast as a ubiquitin-E1-like enzyme;this function is conserved in the mammalian homolog.In mammalian cells,APG7 is essential for autophagy conjugation systems,autophagosome formation,starvation-induced bulk degradation of proteins and organelles.It has been suggested that caspase-8 may alter APG7 levels and thus the APG7 program of autophagic cell death. |
Uniprot ID | O95352 |
基因名全称 | ATG7 autophagy related 7 homolog (S.cerevisiae) |
蛋白名全称 | ATG7 autophagy related 7 homolog (S.cerevisiae) |
推荐稀释比 | APG7 antibody can be used for the detection of APG7 by Western blot at 0.5 ~ 2μg/mL.Antibody can also be used for immunocytochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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